Abstract
A convenient and practical synthesis of valiolamine (4) and its related carbaglycosylamine glycosidase inhibitors from (-)-vibo-quercitol (13), a compound readily produced by biogenesis of myo-inositol (9), is described.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Enzyme Inhibitors / chemical synthesis*
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Enzyme Inhibitors / metabolism
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Enzyme Inhibitors / pharmacology
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Glycoside Hydrolases / antagonists & inhibitors*
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Inositol / analogs & derivatives*
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Inositol / chemical synthesis
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Inositol / chemistry
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Inositol / metabolism
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Inositol / pharmacology
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Molecular Structure
Substances
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Enzyme Inhibitors
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vibo-quercitol
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Inositol
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valiolamine
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Glycoside Hydrolases